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Lancet neurology, 2022-11, Vol.21 (11), p.1004-1060
2022
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Details

Autor(en) / Beteiligte
Titel
Traumatic brain injury: progress and challenges in prevention, clinical care, and research
Ist Teil von
  • Lancet neurology, 2022-11, Vol.21 (11), p.1004-1060
Ort / Verlag
England: Elsevier Ltd
Erscheinungsjahr
2022
Quelle
MEDLINE
Beschreibungen/Notizen
  • InTBIR studies have shown that measurement of blood-based biomarkers adds value to previously proposed clinical decision rules, holding the potential to improve efficiency while reducing radiation exposure. Advanced MRI, including diffusion tensor imaging and volumetric analyses, can identify additional injuries not detectable by visual inspection of standard clinical MR images. [...]the absence of CT abnormalities does not exclude structural damage—an observation relevant to litigation procedures, to management of mild TBI, and when CT scans are insufficient to explain the severity of the clinical condition. In the intensive care setting, automated analysis of blood pressure and intracranial pressure with calculation of derived parameters can help individualise management of TBI. TBI affects multiple domains of functioning, and outcomes are affected by personal characteristics and life-course events, consistent with a multifactorial bio-psycho-socio-ecological model of TBI, as presented in the US National Academies of Sciences, Engineering, and Medicine (NASEM) 2022 report.

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