The New England journal of medicine, 2018-04, Vol.378 (15), p.1408-1418
2018
Volltextzugriff (PDF)
Details
- Autor(en) / Beteiligte
- Titel
- Apalutamide Treatment and Metastasis-free Survival in Prostate Cancer
- Ist Teil von
- The New England journal of medicine, 2018-04, Vol.378 (15), p.1408-1418
- Ort / Verlag
- United States: Massachusetts Medical Society
- Erscheinungsjahr
- 2018
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Among men with nonmetastatic prostate cancer who had a rapid PSA doubling time and were receiving androgen-deprivation therapy, the median metastasis-free survival was 40.5 months with apalutamide versus 16.2 months with placebo. Rash occurred in 24% of men receiving apalutamide.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0028-4793, 1533-4406eISSN: 1533-4406DOI: 10.1056/NEJMoa1715546Titel-ID: cdi_swepub_primary_oai_prod_swepub_kib_ki_se_138001194
- Format
- –
- Schlagworte
- 80 and over, Adenocarcinoma, Adenocarcinoma - drug therapy, Adenocarcinoma - secondary, adverse effects, Aged, Aged, 80 and over, Androgen Antagonists, Androgen Antagonists - adverse effects, Androgen Antagonists - therapeutic use, Androgen receptors, Androgens, Antigens, Care and treatment, Castration, Castration-Resistant, chemically induced, Disease Progression, Disease-Free Survival, Double-Blind Method, drug therapy, Exanthema, Exanthema - chemically induced, Family medical history, Hospitals, Humans, Hypothyroidism, Lymphatic system, Male, Medical imaging, Medical research, Medicin och hälsovetenskap, Metastases, Metastasis, Middle Aged, Neoplasm Metastasis, Neoplasm Metastasis - prevention & control, pathology, Patients, prevention & control, Proportional Hazards Models, Prostate cancer, Prostate-Specific Antigen, Prostatic Neoplasms, Prostatic Neoplasms, Castration-Resistant - drug therapy, Prostatic Neoplasms, Castration-Resistant - pathology, R&D, Research & development, secondary, Survival, therapeutic use, Thiohydantoins, Thiohydantoins - adverse effects, Thiohydantoins - therapeutic use, Urologi och njurmedicin, Urology and Nephrology