Details

Autor(en) / Beteiligte

• Götberg, Matthias
• Christiansen, Evald H
• Gudmundsdottir, Ingibjörg J
• Sandhall, Lennart
• Danielewicz, Mikael
• Jakobsen, Lars
• Olsson, Sven-Erik
• Öhagen, Patrik
• Olsson, Hans
• Omerovic, Elmir
• Calais, Fredrik
• Lindroos, Pontus
• Maeng, Michael
• Tödt, Tim
• Venetsanos, Dimitrios
• James, Stefan K
• Kåregren, Amra
• Nilsson, Margareta
• Carlsson, Jörg
• Hauer, Dario
• Jensen, Jens
• Karlsson, Ann-Charlotte
• Panayi, Georgios
• Erlinge, David
• Fröbert, Ole

Titel

Instantaneous Wave-free Ratio versus Fractional Flow Reserve to Guide PCI

Ist Teil von

• The New England journal of medicine, 2017-05, Vol.376 (19), p.1813-1823

Ort / Verlag

United States: Massachusetts Medical Society

Erscheinungsjahr

2017

Link zum Volltext

Quelle

Free E-Journal (出版社公開部分のみ）

Beschreibungen/Notizen

• In a randomized trial, patients with coronary artery disease underwent PCI guided by either the instantaneous wave-free ratio or fractional flow reserve. At 1 year, iFR-guided PCI was noninferior to FFR-guided PCI with respect to the rate of major adverse cardiac events. Coronary revascularization is warranted only if a patient has one or more coronary-artery stenoses that are hemodynamically important. Large randomized studies have shown that fractional flow reserve (FFR) is superior to angiographic assessment for the detection of hemodynamically important coronary-artery stenoses and that use of FFR to guide coronary revascularization improves clinical outcomes. 1 – 3 FFR is measured by advancing a coronary-pressure guidewire distal to a stenotic lesion and then administering adenosine to assess the pressure gradient across the lesion during hyperemia. Studies have shown that resting indexes (derived from the pressure measurement at rest, without the administration of adenosine) have . . .