Details

Autor(en) / Beteiligte

• Kong, Heidi H.
• Andersson, Björn
• Clavel, Thomas
• Common, John E.
• Jackson, Scott A.
• Olson, Nathan D.
• Segre, Julia A.
• Traidl-Hoffmann, Claudia

Titel

Performing Skin Microbiome Research: A Method to the Madness

Ist Teil von

• Journal of investigative dermatology, 2017-03, Vol.137 (3), p.561-568

Ort / Verlag

United States: Elsevier Inc

Erscheinungsjahr

2017

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• Growing interest in microbial contributions to human health and disease has increasingly led investigators to examine the microbiome in both healthy skin and cutaneous disorders, including acne, psoriasis, and atopic dermatitis. The need for common language, effective study design, and validated methods is critical for high-quality standardized research. Features, unique to skin, pose particular challenges when conducting microbiome research. This review discusses microbiome research standards and highlights important factors to consider, including clinical study design, skin sampling, sample processing, DNA sequencing, control inclusion, and data analysis.