Nature reviews. Neuroscience, 2014-12, Vol.15 (12), p.786-801
2014
Details
- Autor(en) / Beteiligte
- Titel
- Programming of neural cells by (endo)cannabinoids: from physiological rules to emerging therapies
- Ist Teil von
- Nature reviews. Neuroscience, 2014-12, Vol.15 (12), p.786-801
- Ort / Verlag
- England: Nature Publishing Group
- Erscheinungsjahr
- 2014
- Link zum Volltext
- Quelle
- Psychology and Behavioral Sciences Collection
- Beschreibungen/Notizen
- Among the many signalling lipids, endocannabinoids are increasingly recognized for their important roles in neuronal and glial development. Recent experimental evidence suggests that, during neuronal differentiation, endocannabinoid signalling undergoes a fundamental switch from the prenatal determination of cell fate to the homeostatic regulation of synaptic neurotransmission and bioenergetics in the mature nervous system. These studies also offer novel insights into neuropsychiatric disease mechanisms and contribute to the public debate about the benefits and the risks of cannabis use during pregnancy and in adolescence.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1471-003X, 1471-0048eISSN: 1471-0048DOI: 10.1038/nrn3846Titel-ID: cdi_swepub_primary_oai_prod_swepub_kib_ki_se_130212727
- Format
- –
- Schlagworte
- Animals, Axons, Cannabis - adverse effects, Cell differentiation, Cell Differentiation - drug effects, Cell Differentiation - physiology, Cellular signal transduction, Endocannabinoids, Endocannabinoids - metabolism, Female, Growth, Humans, Medicin och hälsovetenskap, Neurogenesis - drug effects, Neurogenesis - physiology, Neurons - cytology, Neurons - drug effects, Neurons - metabolism, Observations, Physiological aspects, Pregnancy