Details

Autor(en) / Beteiligte

• De Bruyne, Bernard
• Fearon, William F
• Pijls, Nico H.J
• Barbato, Emanuele
• Tonino, Pim
• Piroth, Zsolt
• Jagic, Nikola
• Mobius-Winckler, Sven
• Rioufol, Gilles
• Witt, Nils
• Kala, Petr
• MacCarthy, Philip
• Engström, Thomas
• Oldroyd, Keith
• Mavromatis, Kreton
• Manoharan, Ganesh
• Verlee, Peter
• Frobert, Ole
• Curzen, Nick
• Johnson, Jane B
• Limacher, Andreas
• Nüesch, Eveline
• Jüni, Peter

Titel

Fractional Flow Reserve–Guided PCI for Stable Coronary Artery Disease

Ist Teil von

• The New England journal of medicine, 2014-09, Vol.371 (13), p.1208-1217

Ort / Verlag

Waltham, MA: Massachusetts Medical Society

Erscheinungsjahr

2014

Quelle

MEDLINE

Beschreibungen/Notizen

• In this study, fractional flow reserve was used to identify patients with high-risk coronary stenoses, who received either PCI or medical therapy alone; patients with lower-risk lesions were entered in a registry. The PCI group had better outcomes than the medical-therapy group. The benefit of percutaneous coronary intervention (PCI) as an initial treatment strategy in patients with stable coronary artery disease remains controversial. 1 – 3 The potential result from revascularization depends on the extent and the degree of myocardial ischemia. 4 , 5 A fractional flow reserve (FFR) value of 0.80 or less (i.e., a drop in maximal blood flow of 20% or more caused by stenosis), as measured with the use of a coronary pressure wire during catheterization, indicates the potential of a stenosis to induce myocardial ischemia. 6 – 8 In such cases, robust clinical-outcome data favor FFR-guided revascularization, as compared with revascularization guided by . . .