Details

Autor(en) / Beteiligte

• Forshaw, Thomas Richard Johansen
• Ahmed, Hassan Javed
• Kjær, Troels Wesenberg
• Andréasson, Sten
• Sørensen, Torben Lykke

Titel

Full‐field Electroretinography in Age‐related Macular Degeneration: can retinal electrophysiology predict the subjective visual outcome of cataract surgery?

Ist Teil von

• Acta ophthalmologica (Oxford, England), 2020-11, Vol.98 (7), p.693-700

Ort / Verlag

England: Wiley Subscription Services, Inc

Erscheinungsjahr

2020

Link zum Volltext

Quelle

Wiley Online Library Journals Frontfile Complete

Beschreibungen/Notizen

• Purpose Predicting the visual gain from cataract surgery when the main cause of vision loss is age‐related macular degeneration may be difficult and warrants the need for an objective predictor of subjective outcome. Full‐field electroretinography is an objective measure of overall retinal function. We therefore wanted to study if full‐field electroretinography can predict subjective visual outcome using visual function questionnaire. Methods Thirty‐one patients with age‐related macular degeneration operated for bilateral cataract underwent full‐field electroretinography preoperatively. Full‐field electroretinography was performed according to International Society for the Clinical Electrophysiology of Vision standards using a Ganzfeld bowl (RETI‐port/scan 21, Roland, Berlin) and Dawson–Trick–Litzkow fibre electrodes. Vision‐related quality of life was measured using the National Eye Institute Visual Function Questionnaire‐39 before first‐eye surgery and 4.12 ± 2.11 months after second‐eye surgery. Results Mean change in composite visual function questionnaire score after cataract surgery was 9.2 ± 11.9. The patients were divided into three groups: visual function questionnaire composite score increase >10 (n = 17); no change (n = 8); and decrease (n = 6). In the dark‐adapted full‐field electroretinography responses, we found a significant difference between the three groups in the 0.01 b‐wave amplitude (p = 0.05), the 10.0 b‐wave amplitude (p = 0.04) and a near‐significant difference in 3.0 a‐wave amplitude (p = 0.09). Other dark‐adapted responses (the 3.0 b‐wave and 10.0 a‐wave) did not show any significant differences between the three groups, and neither did the light‐adapted responses. Conclusion Patients with low dark‐adapted responses on full‐field electroretinography preoperatively experience a decrease in subjective vision‐related quality of life, suggesting that maintained rod function before cataract surgery may be important.