Details

Autor(en) / Beteiligte

• Siikanen, J.
• Ohlsson, T.
• Medema, J.
• Van-Essen, J.
• Sandell, A.

Titel

A niobium water target for routine production of [18F]Fluoride with a MC 17 cyclotron

Ist Teil von

• Applied radiation and isotopes, 2013-02, Vol.72, p.133-136

Ort / Verlag

England: Elsevier Ltd

Erscheinungsjahr

2013

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• A [18F]Fluoride water target was constructed for a Scanditronix MC 17 cyclotron, without a beam line, with a typical wide beam of ∼30×5mm2. Niobium was used as target chamber material. One hour irradiation with 45μA protons yields about 110GBq [18F]Fluoride. The saturation yield is 8.0±0.6GBq/μA (EOB). The FDG yield is 60±5% (EOS) with a TracerLab MX (G.E. Healthcare). More than 100GBq FDG is routinely produced after a 2h irradiation. ► A [18F]Fluoride water target was constructed for a MC 17 cyclotron. ► Chemically inert niobium was used as target chamber.► Produced [18F]Fluoride was tested by making more than thousand FDG batches. ► Saturation yield is 8.0±0.6GBq/μA and FDG yield is 60±5%.