Details

Autor(en) / Beteiligte

• Wu, Frederick C.W
• Tajar, Abdelouahid
• Beynon, Jennifer M
• Pye, Stephen R
• Silman, Alan J
• Finn, Joseph D
• O'Neill, Terence W
• Bartfai, Gyorgy
• Casanueva, Felipe F
• Forti, Gianni
• Giwercman, Aleksander
• Han, Thang S
• Kula, Krzysztof
• Lean, Michael E.J
• Pendleton, Neil
• Punab, Margus
• Boonen, Steven
• Vanderschueren, Dirk
• Labrie, Fernand
• Huhtaniemi, Ilpo T

Titel

Identification of Late-Onset Hypogonadism in Middle-Aged and Elderly Men

Ist Teil von

• 88th Annual Meeting of the Endocrine-Society,2006-06-24 - 2006-06-27, 2010-07, Vol.363 (2), p.123-135

Ort / Verlag

Waltham, MA: Massachusetts Medical Society

Erscheinungsjahr

2010

Link zum Volltext

Quelle

Elektronische Zeitschriftenbibliothek

Beschreibungen/Notizen

• The investigators sought evidence-based criteria for identifying late-onset hypogonadism in men between the ages of 40 and 79 years on the basis of the association between symptoms and a low testosterone level. The data suggest that late-onset hypogonadism can be defined by the presence of at least three sexual symptoms with a total testosterone level of less than 11 nmol per liter and a free testosterone level of less than 220 pmol per liter. The data suggest that late-onset hypogonadism can be defined by the presence of at least three sexual symptoms with a total testosterone level of less than 11 nmol per liter and a free testosterone level of less than 220 pmol per liter. The clinical importance of an age-related reduction in the testosterone level 1 – 3 remains controversial. 4 , 5 Because of the uncertainty regarding the nature of testosterone deficiency in aging men, 6 – 9 recent guidelines have suggested that so-called late-onset hypogonadism be regarded as a clinical and biochemical state with advancing age, characterized by particular symptoms and a low level of serum testosterone. 10 , 11 However, few data on hypogonadism in aging men are available 4 , 8 , 12 because of the lack of evidence regarding the exact criteria for identifying testosterone deficiency in older men who do not have pathological hypogonadism. 6 , 13 Although a familiar array . . .