Details

Autor(en) / Beteiligte

• Ersbøll, Anne S.
• Hedegaard, Mette
• Damm, Peter
• Johansen, Marianne
• Tabor, Ann
• Hegaard, Hanne K.

Titel

Changes in the pattern of paracetamol use in the periconception period in a Danish cohort

Ist Teil von

• Acta obstetricia et gynecologica Scandinavica, 2015-08, Vol.94 (8), p.898-903

Ort / Verlag

United States: Blackwell Publishing Ltd

Erscheinungsjahr

2015

Link zum Volltext

Quelle

Taylor & Francis Journals Auto-Holdings Collection

Beschreibungen/Notizen

• Paracetamol is the most commonly used over‐the‐counter drug in pregnancy. It is generally considered to be safe, but prolonged antenatal exposure has been associated with offspring short‐ and long‐term morbidity. Our aim was to describe the pattern of paracetamol use with a focus on frequent ingestion (more than once a week), 3 months before and in early pregnancy. In this cohort, 8650 pregnant women responded to a web‐based clinical questionnaire that included questions about drug use. Paracetamol was the most used drug before and in early pregnancy (35.2% and 6.5% of respondents, respectively). The proportion of frequent users decreased from 3.9% before to 0.9% in early pregnancy. Frequent paracetamol use was associated with smoking, co‐morbidities, body mass index ≥25 kg/m2, unplanned pregnancy, no education and inability to understand Danish. A significant decrease in the proportion of women with any paracetamol use in early pregnancy was noted after access to large packs was restricted by legislation.