Details

Autor(en) / Beteiligte

• Bonjer, H. Jaap
• Deijen, Charlotte L
• Abis, Gabor A
• Cuesta, Miguel A
• van der Pas, Martijn H.G.M
• de Lange-de Klerk, Elly S.M
• Lacy, Antonio M
• Bemelman, Willem A
• Andersson, John
• Angenete, Eva
• Rosenberg, Jacob
• Fuerst, Alois
• Haglind, Eva

Titel

A Randomized Trial of Laparoscopic versus Open Surgery for Rectal Cancer

Ist Teil von

• The New England journal of medicine, 2015-04, Vol.372 (14), p.1324-1332

Ort / Verlag

United States: Massachusetts Medical Society

Erscheinungsjahr

2015

Quelle

MEDLINE

Beschreibungen/Notizen

• In a randomized trial involving more than 1000 patients, outcomes including recurrence rate and overall survival were similar among patients undergoing laparoscopic surgery and those undergoing open surgery. Colorectal cancer is the third most common cancer worldwide and accounts for nearly 1.4 million new cases and 694,000 deaths per year. Approximately one third of all colorectal cancers are localized in the rectum. 1 – 4 Less than a half century ago, rectal cancer had a poor prognosis, with cancer recurrence rates in the pelvic or perineal area (locoregional recurrence) of up to 40% and 5-year survival rates after surgical resection of less than 50%. 5 , 6 In the 1980s, Heald and Ryall 6 introduced a new surgical technique of complete removal of the fatty envelope surrounding the rectum (mesorectum), called total mesorectal . . .