Details

Autor(en) / Beteiligte

• Acosta Ruiz, Vanessa
• Lönnemark, Maria
• Brekkan, Einar
• Dahlman, Pär
• Wernroth, Lisa
• Magnusson, Anders

Titel

Predictive factors for complete renal tumor ablation using RFA

Ist Teil von

• Acta radiologica (1987), 2016-07, Vol.57 (7), p.886-893

Ort / Verlag

London, England: SAGE Publications

Erscheinungsjahr

2016

Quelle

Taylor & Francis Journals Auto-Holdings Collection

Beschreibungen/Notizen

• Background Radiofrequency ablation (RFA) can be used to treat renal masses in patients where surgery is preferably avoided. As tumor size and location can affect ablation results, procedural planning needs to identify these factors to limit treatment to a single session and increase ablation success. Purpose To identify factors that may affect the primary efficacy of complete renal tumor ablation with radiofrequency after a single session. Material and Methods Percutaneous RFA (using an impedance based system) was performed using computed tomography (CT) guidance. Fifty-two renal tumors (in 44 patients) were retrospectively studied (median follow-up, 7 months). Data collection included patient demographics, tumor data (modified Renal Nephrometry Score, histopathological diagnosis), RFA treatment data (electrode placement), and follow-up results (tumor relapse). Data were analyzed through generalized estimating equations. Results Primary efficacy rate was 83%. Predictors for complete ablation were optimal electrode placement (P = 0.002, OR = 16.67) and increasing distance to the collecting system (P = 0.02, OR = 1.18). Tumor size was not a predictor for complete ablation (median size, 24 mm; P = 0.069, OR = 0.47), but all tumors ≤2 cm were completely ablated. All papillary tumors and oncocytomas were completely ablated in a single session; the most common incompletely ablated tumor type was clear cell carcinoma (6 of 9). Conclusion Optimal electrode placement and a long distance from the collecting system are associated with an increased primary efficacy of renal tumor RFA. These variables need to be considered to increase primary ablation success. Further studies are needed to evaluate the effect of RFA on histopathologically different renal tumors.