Nature biotechnology, 2021-04, Vol.39 (4), p.499-509
- Nayfach, Stephen
- Roux, Simon
- Seshadri, Rekha
- Udwary, Daniel
- Varghese, Neha
- Schulz, Frederik
- Wu, Dongying
- Paez-Espino, David
- Chen, I-Min
- Huntemann, Marcel
- Palaniappan, Krishna
- Ladau, Joshua
- Mukherjee, Supratim
- Reddy, T B K
- Nielsen, Torben
- Kirton, Edward
- Faria, José P
- Edirisinghe, Janaka N
- Henry, Christopher S
- Jungbluth, Sean P
- Chivian, Dylan
- Dehal, Paramvir
- Wood-Charlson, Elisha M
- Arkin, Adam P
- Tringe, Susannah G
- Visel, Axel
- Woyke, Tanja
- Mouncey, Nigel J
- Ivanova, Natalia N
- Kyrpides, Nikos C
- Eloe-Fadrosh, Emiley A
2021
Details
- Autor(en) / Beteiligte
- Nayfach, Stephen
- Roux, Simon
- Seshadri, Rekha
- Udwary, Daniel
- Varghese, Neha
- Schulz, Frederik
- Wu, Dongying
- Paez-Espino, David
- Chen, I-Min
- Huntemann, Marcel
- Palaniappan, Krishna
- Ladau, Joshua
- Mukherjee, Supratim
- Reddy, T B K
- Nielsen, Torben
- Kirton, Edward
- Faria, José P
- Edirisinghe, Janaka N
- Henry, Christopher S
- Jungbluth, Sean P
- Chivian, Dylan
- Dehal, Paramvir
- Wood-Charlson, Elisha M
- Arkin, Adam P
- Tringe, Susannah G
- Visel, Axel
- Woyke, Tanja
- Mouncey, Nigel J
- Ivanova, Natalia N
- Kyrpides, Nikos C
- Eloe-Fadrosh, Emiley A
- Titel
- A genomic catalog of Earth's microbiomes
- Ist Teil von
- Nature biotechnology, 2021-04, Vol.39 (4), p.499-509
- Ort / Verlag
- United States: Nature Publishing Group
- Erscheinungsjahr
- 2021
- Link zum Volltext
- Beschreibungen/Notizen
- The reconstruction of bacterial and archaeal genomes from shotgun metagenomes has enabled insights into the ecology and evolution of environmental and host-associated microbiomes. Here we applied this approach to >10,000 metagenomes collected from diverse habitats covering all of Earth's continents and oceans, including metagenomes from human and animal hosts, engineered environments, and natural and agricultural soils, to capture extant microbial, metabolic and functional potential. This comprehensive catalog includes 52,515 metagenome-assembled genomes representing 12,556 novel candidate species-level operational taxonomic units spanning 135 phyla. The catalog expands the known phylogenetic diversity of bacteria and archaea by 44% and is broadly available for streamlined comparative analyses, interactive exploration, metabolic modeling and bulk download. We demonstrate the utility of this collection for understanding secondary-metabolite biosynthetic potential and for resolving thousands of new host linkages to uncultivated viruses. This resource underscores the value of genome-centric approaches for revealing genomic properties of uncultivated microorganisms that affect ecosystem processes.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1087-0156, 1546-1696eISSN: 1546-1696DOI: 10.1038/s41587-020-0718-6Titel-ID: cdi_swepub_primary_oai_DiVA_org_su_186583
- Format
- –
- Schlagworte
- Agricultural engineering, Agricultural land, Air Microbiology, Animals, Archaea, Archaea - classification, Archaea - genetics, Archaea - isolation & purification, Bacteria, Bacteria - classification, Bacteria - genetics, Bacteria - isolation & purification, BASIC BIOLOGICAL SCIENCES, Biological and medical sciences, Environmental sciences, Biosphere, Candidate species, Cataloging, Catalogs as Topic, Comparative analysis, Computational biology and bioinformatics, Design and construction, Earth, Ecosystem, Environmental engineering, Environmental Studies, Genetic aspects, Genomes, Genomic libraries, Genomics, Humans, Life Sciences, Metabolism, Metabolites, Metabolomics, Metabolomics - methods, Metagenome, Metagenomics, Metagenomics - methods, Methods, Microbial colonies, Microbiology, Microbiomes, Microorganisms, Miljövetenskapliga studier, Oceans, Phylogenetics, Phylogeny, Resource, Soil Microbiology, Varieties, Viruses, Viruses - genetics, Viruses - isolation & purification, Water Microbiology