Details

Autor(en) / Beteiligte

• Agranovsky, A. A.

Titel

Closteroviruses: Molecular Biology, Evolution and Interactions with Cells

Ist Teil von

• Plant Viruses: Evolution and Management, 2016, p.231-252

Ort / Verlag

Singapore: Springer Singapore Pte. Limited

Erscheinungsjahr

2016

Link zum Volltext

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Family Closteroviridae combines about 40 positive-strand RNA viruses infecting higher plants. Closteroviruses have several distinguishing traits: (i) semi-persistent mode of insect transmission (implying that a virus is retained within a vector for hours) and phloem-limited nature of virus infection; (ii) unique structure of elongated particles with spiral type of symmetry built of several virus proteins; (iii) large RNA genomes of up to 20 kb, a value close to the largest positive-strand RNA genomes of animal nidoviruses; (iv) the presence of a gene homologous to the HSP70 family of cell chaperones; and (iv) the presence of a number of duplicated and diverged genes (or parts thereof), e.g. the genes for the major and minor capsid protein (CP). The genome expression of closteroviruses occurs by proteolytic processing and +1 ribosomal frameshifting for the replication-associated products of the 5′ -proximal genes, whereas the 3′-terminal genes are expressed via a nested set of subgenomic mRNAs. This strikingly resembles the expression strategy of nidoviruses. Besides fundamental interest to the molecular biology and evolution of the large RNA genomes, it is important that some closteroviruses cause grave diseases in cultivated crops like citrus trees, sugar beet, and tomato. This makes the studies of closterovirus molecular biology and interactions with cells important in the applied aspect.