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Training load is one of multiple risk factors for sustaining an injury in football. Training workloads are applied to athletes with the goal of inducing positive physiological changes and maximizing performance. The various biological adaptations induced by (appropriate) training increase athletes’ capacity to accept and withstand load and may thus provide protection from injuries. The aim of load management is thus to optimally configure training, competition, and other loads to maximize adaptation and performance with a minimal risk of injury. This chapter will focus on the established evidence of training load and injury risk in football and how monitoring training load may help to prevent injuries.