Details

Autor(en) / Beteiligte

• Dreher, Mark L

Titel

Insights on the Role of Fiber in Colonic Microbiota Health

Ist Teil von

• Dietary Fiber in Health and Disease, 2017, p.41-66

Ort / Verlag

Switzerland: Springer International Publishing AG

Erscheinungsjahr

2017

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• The diet has been estimated to contribute to as much as 60% of microbiota composition variation with fiber and animal products being the most influential food components. Fiber is the primary energy source for maintenance of a healthy bacterial community and source of bioactive fermentation metabolites such as short-chain fatty acids (SCFAs), especially butyrate, which is important for attenuating colonic and systemic inflammation for human health, including maintaining the colonic protective barrier against pathogenic bacteria. Changing from a low fiber, meat based diet to a high fiber, plant based diet can significantly improve microbiota health within 24 hrs, but it may take over 10 days for major changes in primary enterotype identity to occur. Western diets which contain approximately half of the recommended adequate intake levels of fiber, have led to a fiber which gap is a major factor responsible for microbiota dysbiosis, which predisposes individuals to increased colonic and systemic inflammation, insulin resistance associated with many chronic diseases, and increased frailty in older age. Numerous intervention trials show that the increased intake of fiber-rich whole foods, fiber ingredients, or supplements such as prebiotics support a healthier microbiota ecosystem