Details

Autor(en) / Beteiligte

• Gancheva, Veska
• Stoev, Hristo
• Rojas, Fernando
• Ortuño, Francisco
• Rojas, Ignacio
• Valenzuela, Olga

Titel

DNA Sequence Alignment Method Based on Trilateration

Ist Teil von

• Bioinformatics and Biomedical Engineering, p.271-283

Ort / Verlag

Cham: Springer International Publishing

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• The effective comparison of biological data sequences is an important and a challenging task in bioinformatics. The sequence alignment process itself is a way of arranging DNA sequences in order to identify similar areas that may have a consequence of functional, structural or evolutionary relations between them. A new effective and unified method for sequence alignment on the basic of trilateration, called CAT method, and using C (cytosine), A (adenine) and T (thymine) benchmarks is presented in this paper. This method suggests solutions to three major problems in sequence alignment: creating a constant favorite sequence, reducing the number of comparisons with the favorite sequence, and unifying/standardizing the favorite sequence by defining benchmark sequences.