Details

Autor(en) / Beteiligte

• Beddhu, Srinivasan
• Kwan, Bonnie Ching-Ha

Titel

Adiposity and Kidney Disease

Ist Teil von

• Adipose Tissue and Adipokines in Health and Disease, p.351-358

Ort / Verlag

Totowa, NJ: Humana Press

Link zum Volltext

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• The prevalence of chronic kidney disease is growing worldwide. Epidemiological data suggest there is a causal relationship with adiposity. There are also laboratory research and clinical studies showing that adiposity is involved in the development and the progression of kidney disease itself. Mechanisms include adaptation to increased body mass, activation of sympathetic nervous and renin-angiotensin systems, effects of insulin resistance, lipid overload, and release of adipokines. Kidney disease may also affect the association of adiposity with cardiovascular outcomes. In this chapter, the interactions of adiposity and kidney disease and their effects on clinical outcomes are examined.