Details

Autor(en) / Beteiligte

• Bhullar, Deepika
• Nemazee, David
• Burton, Dennis R
• Hangartner, Lars
• Burton, Dennis R.

Titel

B Cells Carrying Antigen Receptors Against Microbes as Tools for Vaccine Discovery and Design

Ist Teil von

• Vaccination Strategies Against Highly Variable Pathogens, 2020, Vol.428, p.165-180

Ort / Verlag

Switzerland: Springer International Publishing AG

Erscheinungsjahr

2020

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Can basic science improve the art of vaccinology? Here, we review efforts to understand immune responses with the aim to improve vaccine design and, eventually, to predict the efficacy of human vaccine candidates using the tools of transformed B cells and targeted transgenic mice carrying B cells with antigen receptors specific for microbes of interest.