Details

Autor(en) / Beteiligte

• Garmes, Heraldo Mendes
• Boguszewski, César Luiz
• Miranda, Paulo Augusto Carvalho
• Martins, Manoel Ricardo Alves
• da Silva, Silvia Regina Correa
• Abucham, Filho, Julio Zaki
• de Castro Musolino, Nina Rosa
• Vilar, Lucio
• Portari, Luiz Henrique Corrêa
• Gadelha, Mônica Roberto
• Kasuki, Leandro
• Naves, Luciana Ansaneli
• Czepielewski, Mauro Antônio
• de Almeida, Tobias Skrebsky
• Duarte, Felipe Henning Gaia
• Glezer, Andrea
• Bronstein, Marcello Delano

Titel

Management of hypopituitarism: a perspective from the Brazilian Society of Endocrinology and Metabolism

Ist Teil von

• Archives of Endocrinology and Metabolism, 2021-03, Vol.65 (2), p.212-230

Ort / Verlag

Brazil: Sociedade Brasileira de Endocrinologia e Metabologia

Erscheinungsjahr

2021

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• Hypopituitarism is a disorder characterized by insufficient secretion of one or more pituitary hormones. New etiologies of hypopituitarism have been recently described, including head trauma, cerebral hemorrhage, and drug-induced hypophysitis. The investigation of patients with these new disorders, in addition to advances in diagnosis and treatment of hypopituitarism, has increased the prevalence of this condition. Pituitary hormone deficiencies can induce significant clinical changes with consequent increased morbidity and mortality rates, while hormone replacement based on current guidelines protects these patients. In this review, we will first discuss the different etiologies of hypopituitarism and then address one by one the clinical aspects, diagnostic evaluation, and therapeutic options for deficiencies of TSH, ACTH, gonadotropin, and GH. Finally, we will detail the hormonal interactions that occur during replacement of pituitary hormones.