Details

Autor(en) / Beteiligte

• Murgu, Michael
• Santos, Luiz F. Arruda
• Souza, Gezimar D. de
• Daolio, Cristina
• Schneider, Bernd
• Ferreira, Antônio Gilberto
• Rodrigues-Filho, Edson

Titel

Hydroxylation of a hederagenin derived saponin by a Xylareaceous fungus found in fruits of Sapindus saponaria

Ist Teil von

• Journal of the Brazilian Chemical Society, 2008, Vol.19 (5), p.831-835

Ort / Verlag

Sociedade Brasileira de Química

Erscheinungsjahr

2008

Link zum Volltext

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• During our screening of tropical plants for endophyte microorganisms, a Xylareaceous fungus was found living on the internal part of Sapindus saponaria fruits. The fruits of S. saponaria accumulate great amounts of triterpenoidal and sesquiterpenoidal saponins. The saponin 3-O-(β-D-xylopyranosyl)-(1→3)-α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranosyl-hederagenin was isolated using chromatographic methods, after alkaline hydrolysis of the crude extract obtained from S. saponaria fruits and added to the culture medium used to grows the fungus. A new saponin was isolated from this experiment by preparative scale HPLC and characterized as a 22α-hydroxy derivative. The structure of this hydroxylated saponin was elucidated based on interpretation of MS/MS data and NMR spectra.