Details

Autor(en) / Beteiligte

• Oliveira, Rafael R. B.
• Góis, Rebecca M. O.
• Siqueira, Rosana S.
• Almeida, Jackson R. G. S.
• Lima, Julianeli T.
• Nunes, Xirley P.
• Oliveira, Viseldo R.
• Siqueira, Jullyana S.
• Quintans-Júnior, Lucindo J.

Titel

Antinociceptive effect of the ethanolic extract of Amburana cearensis (Allemão) A.C. Sm., Fabaceae, in rodents

Ist Teil von

• Revista brasileira de farmacognosia, 2009-09, Vol.19 (3), p.672-676

Ort / Verlag

Sociedade Brasileira de Farmacognosia

Erscheinungsjahr

2009

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• The ethanolic extract of the trunk bark of Amburana cearensis (EEA) was examined for its oral (p.o.) analgesic activity at the doses of 100, 200 and 400 mg/kg body weight. In the acetic acid-induced writhing test, the EEA (200 and 400 mg/kg, p.o.) reduced the number of writhing by 33.4% and 40.7%, respectively. Additionally, EEA (100, 200 and 400 mg/kg, p.o.) decreased by 77.5%, 79.7 and 91.3%, respectively, the paw liking time in the second phase of the formalin test. Therefore, EEA showed a dose-dependent analgesic effect in formalin test and was effective in reducing writhing in mice.