Details

Autor(en) / Beteiligte

• MIRANDA C., MARCELO
• BUSTAMANTE C., M. LEONOR

Titel

Hierro intravenoso en la terapia del síndrome de piernas inquietas

Ist Teil von

• Revista medíca de Chile, 2019-12, Vol.147 (12), p.1569-1571

Ort / Verlag

Sociedad Médica de Santiago

Erscheinungsjahr

2019

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• Restless legs syndrome (RLS) may severely affect the quality of life of patients. A deficient iron incorporation into the central nervous system has an important role in the pathophysiology of RLS. Severely affected patients may not respond to current therapeutic options. We report a preliminary experience with five patients with severe RLS and low serum ferritin levels who did not improve with oral iron. All were treated with 1 g of intravenous iron carboxymaltose. They experienced a marked improvement in symptoms, evident even during the first week of therapy that had persistent after up to two years of follow-up. A significant change in the RLS severity scale was observed after intravenous iron. Serum ferritin levels increased in all of them. Intravenous iron could be a therapeutic option for patients with severe RLS.