Details

Autor(en) / Beteiligte

• Qi, Ming
• Xu, An-Wu

Titel

A visible-light-induced photosensitizer-free decarbonylative Minisci-type reaction

Ist Teil von

• Organic & biomolecular chemistry, 2024-03, Vol.22 (13), p.2654-2661

Ort / Verlag

England: Royal Society of Chemistry

Erscheinungsjahr

2024

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• This study presents a green and practical visible-light-induced photosensitizer-free decarbonylative Minisci-type reaction using aldehydes as alkyl radical precursors. The photocatalytic system exhibits a broad substrate scope and synthetically useful yields. Mechanistic experiments revealed that alkyl radicals could be generated through auto-oxidation of aldehydes under irradiation, which is a mild and effective method for achieving late-stage functionalization of N-heteroarenes. Some biologically active N-heteroarenes could be alkylated using this photocatalytic system smoothly. A photoinduced photosensitizer-free Minisci-type reaction using aldehydes as radical precursors was reported, which showed excellent yields and functional groups tolerance. This effective method could achieve alkylation of natural products smoothly.