Details

Autor(en) / Beteiligte

• Shen, Kunrong
• Feng, Chuan
• Liu, Yilei
• Yi, Dong
• Lin, Peng
• Li, Huifang
• Gong, Yimou
• Wei, Siping
• Fu, Qiang
• Zhang, Zhijie

Titel

Visible light-enabled synthesis of phosphorylated indolizine and pyridoindole derivatives HAT-mediated radical cascade cyclization

Ist Teil von

• Organic & biomolecular chemistry, 2023-12, Vol.21 (47), p.9341-9345

Erscheinungsjahr

2023

Link zum Volltext

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• A visible light-enabled cascade cyclization strategy is disclosed with concomitant phosphorylation and heterocycle construction. It provides a novel and environmentally benign approach for accessing tetrahydroindolizine-containing phosphonates under metal-free conditions. Mechanistic studies revealed that phosphinoyl radicals were generated from H-phosphonates via a HAT process. Phosphinoyl radicals were generated from H-phosphonates via a photocatalytic HAT process and applied to the construction of phosphorylated heterocycles under metal-free conditions.