Details

Autor(en) / Beteiligte

• Li, Lingdong
• Zhang, Songwei
• Du, Zhongtian
• Wang, Hande
• Zhou, Hao

Titel

New cationic linear -chloramines based on -butylamide: chemical synthesis and antibacterial application

Ist Teil von

• New journal of chemistry, 2024-01, Vol.48 (3), p.176-18

Erscheinungsjahr

2024

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• For the first time, we synthesized three types of cationic linear N -chloramines that do not use the popular 5,5-dimethyl hydantoin scaffold. The characterized N -chloramines displayed satisfactory bactericidal activity, and the long-chain analogues exerted greatly elevated biocidal efficacy due to "synergistic" antibacterial actions between the N-Cl moiety and long chain cationic center. Our study provides highly efficacious biocides as well as paving the way for producing novel N -chloramines that exclude toxic cyanide salts. For the first time, cationic linear N -chloramine biocides that do not include 5,5-dimethyl hydantoin scaffolds were synthesized, and their long chain analogues were found to exert greatly elevated biocidal efficacy.