Details

Autor(en) / Beteiligte

• Saha, Sharajit
• Bhattacharyya, Hemanga
• Karjee, Pallab
• Debnath, Bijoy
• Verma, Kshitiz
• Punniyamurthy, Tharmalingam

Titel

Expedient C-H allylation of sulfoxonium ylides: merging C-H and C-C/C-het bond activation

Ist Teil von

• Chemical communications (Cambridge, England), 2023-11, Vol.59 (95), p.14173-14176

Ort / Verlag

Cambridge: Royal Society of Chemistry

Erscheinungsjahr

2023

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Sulfoxonium ylide chelation-assisted C-H allylation of arenes has been accomplished utilizing strained vinyl carbo/heterocycles as the allyl surrogates via sequential C-H and C-C/het bond activation. Broad substrate scope, Co-catalysis, selectivity, and late-stage drug mutation are the important practical features. Merging cobalt-catalyzed C-H activation and ring opening of vinylic strained rings using sulfoxonium ylide as a weak directing group has been accomplished to furnish structurally diverse carbo/hetero allyl scaffolds.