Details

Autor(en) / Beteiligte

• Wu, Qiang
• Liu, Wei
• Wang, Miao
• Huang, Yahao
• Hu, Peng

Titel

Iron-catalyzed deconstructive alkylation through chlorine radical induced C-C single bond cleavage under visible light

Ist Teil von

• Chemical communications (Cambridge, England), 2022-09, Vol.58 (71), p.9886-9889

Ort / Verlag

Cambridge: Royal Society of Chemistry

Erscheinungsjahr

2022

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Selective C-C single bond cleavage of simple compounds is a highly challenging and desired process. Herein, a chlorine radical-induced deconstructive C-C bond alkylation with alcohols and alkenes catalyzed by iron salts was reported for the first time. Readily available alcohols and various electron-deficient alkenes were tolerated. Late-stage and large-scale reactions proceed smoothly. This catalyst system shows potential for diversified deconstructive functionalization of simple C-C bonds. A general method of iron-catalyzed deconstructive alkylation of alcohols with olefins through chlorine radical induced C-C single bond cleavage is developed.