Details

Autor(en) / Beteiligte

• Chen, Tao
• Wang, Aoning
• Zhang, Linxue
• Wei, Chenlong
• Huang, Juhui
• Liu, Xiang
• Fu, Zhenqian

Titel

Formal [4 + 1] annulation of fluorinated sulfonium salt with cyclic unsaturated imines to access CF-substituted pyrroles

Ist Teil von

• Organic & biomolecular chemistry, 2021-04, Vol.19 (14), p.3128-3133

Erscheinungsjahr

2021

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Formal [4 + 1] annulation of easily available fluorinated sulfonium salt with cyclic unsaturated imines has been successfully developed. A structurally diverse set of CF 3 -substituted dihydropyrroles was efficiently constructed in acceptable to excellent yields with excellent diastereoselectivities. The resulting CF 3 -containing dihydropyrroles from this transition metal-free strategy could be easily transformed to pyrroles in good yields under basic conditions. A structurally diverse set of CF 3 -substituted pyrroles was efficiently constructed in acceptable to excellent yields.