Details

Autor(en) / Beteiligte

• Hajiali, Hadi
• Ouyang, Liliang
• Llopis-Hernandez, Virginia
• Dobre, Oana
• Rose, Felicity R. A. J

Titel

Review of emerging nanotechnology in bone regeneration: progress, challenges, and perspectives

Ist Teil von

• Nanoscale, 2021-06, Vol.13 (23), p.1266-128

Ort / Verlag

Cambridge: Royal Society of Chemistry

Erscheinungsjahr

2021

Link zum Volltext

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• The application of nanotechnology to regenerative medicine has increased over recent decades. The development of materials that can influence biology at the nanoscale has gained interest as our understanding of the interactions between cells and biomaterials at the nanoscale has grown. Materials that are either nanostructured or influence the nanostructure of the cellular microenvironment have been developed and shown to have advantages over their microscale counterparts. There are several reviews which have been published that discuss how nanomaterials have been used in regenerative medicine, particularly in bone regeneration. Most of these studies have explored this concept in specific areas, such as the application of glass-based nanocomposites, nanotechnology for targeted drug delivery to stimulate bone repair, and the progress in nanotechnology for the treatment of osteoporosis. In this review paper, the impact of nanotechnology in biomaterials development for bone regeneration will be discussed highlighting specifically, nanostructured materials that influence mechanical properties, biocompatibility, and osteoinductivity. The impact of nanotechnology in biomaterials development for bone regeneration are summarised with a focus on three key areas; mechanical properties, biocompatibility, and osteoinductivity. Current challenges and future directions are also discussed.