Details

Autor(en) / Beteiligte

• Zeng, Fan-Lin
• Xie, Kun-Chen
• Liu, Yu-Ting
• Wang, He
• Yin, Peng-Cheng
• Qu, Ling-Bo
• Chen, Xiao-Lan
• Yu, Bing

Titel

Visible-light-promoted catalyst-/additive-free synthesis of aroylated heterocycles in a sustainable solvent

Ist Teil von

• Green chemistry : an international journal and green chemistry resource : GC, 2022-02, Vol.24 (4), p.1732-1737

Ort / Verlag

Cambridge: Royal Society of Chemistry

Erscheinungsjahr

2022

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• A general visible-light-induced catalyst-/additive-free strategy was developed for the construction of various aroylated heterocycles (55 examples, up to 95% yield, including modification of pharmaceuticals and natural products) such as thioflavones, benzimidazo[2,1- a ]isoquinolin-6(5 H )-ones, indolo[2,1- a ]isoquinolin-6(5 H )ones, quaternary 3,3-dialkyl 2-oxindoles, quinoxalin-2(1 H )-ones, and benzo[ e ][1,2,3]oxathiazine 2,2-dioxides in a green solvent (dimethyl carbonate) under air and room temperature conditions. This practical acylation process was achieved using 4-acyl-1,4-dihydropyridines (acyl-DHPs) as acylating reagents under mild conditions, avoiding the use of catalysts, bases, additional oxidants, and traditional organic solvents. A general visible-light-induced catalyst-/additive-free strategy was developed for the construction of various aroylated heterocyclesunder air and room temperature conditions.