Details

Autor(en) / Beteiligte

• Bondon, Nicolas
• Raehm, Laurence
• Charnay, Clarence
• Boukherroub, Rabah
• Durand, Jean-Olivier

Titel

Nanodiamonds for bioapplications, recent developments

Ist Teil von

• Journal of materials chemistry. B, Materials for biology and medicine, 2020-12, Vol.8 (48), p.1878-1896

Ort / Verlag

England: Royal Society of Chemistry

Erscheinungsjahr

2020

Quelle

MEDLINE

Beschreibungen/Notizen

• The world of biomedical research is in constant evolution, requiring more and more conditions and norms through pre-clinic and clinic studies. Nanodiamonds (NDs) with exceptional optical, thermal and mechanical properties emerged on the global scientific scene and recently gained more attention in biomedicine and bioanalysis fields. Many problematics have been deliberated to better understand their in vitro and in vivo efficiency and compatibility. Light was shed on their synthesis, modification and purification steps, as well as particle size and surface properties in order to find the most suitable operating conditions. In this review, we present the latest advances of NDs use in bioapplications. A large variety of subjects including anticancer and antimicrobial systems, wound healing and tissue engineering management tools, but also bioimaging and labeling probes are tackled. The key information resulting from these recent works were evidenced to make an overview of the potential features of NDs, with a special look on emerging therapeutic and diagnosis combinations. This review describes the very recent bioapplications of nanodiamonds combining nanoparticles and diamond features, underlining their multiple roles in theranostics.