Details

Autor(en) / Beteiligte

• Fréneau, Maxime
• Lefebvre, Corentin
• Gómez Fernández, Mario Andrés
• Richard, Claire
• Hoffmann, Norbert

Titel

Photochemical reactivity of phenyl (methyl-tetrazolyl) ketone - hydrogen atom transfer electron transfer

Ist Teil von

• New journal of chemistry, 2019-11, Vol.43 (44), p.17151-17158

Erscheinungsjahr

2019

Link zum Volltext

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Phenyl (methyl-tetrazolyl) ketone ( 1 ) is a synthesis intermediate of tetrazolyloxime fungicides and can also be generated upon their irradiation. Its photolysis is highly solvent-dependent, which prompted us to investigate the reaction mechanism more deeply. The nanosecond laser flash photolysis of 1 yielded the triplet excited state ( λ max = 390/570 nm) immediately after the pulse. This was later converted into different secondary species that were identified using their specific reactivity as well as product studies. The ketyl radical ( λ max = 315/475 nm) was generated in less than 0.02 μs in a good H-donor solvent such as 2-propanol and in around 0.06 μs in cyclohexane, a medium H-donor solvent. In 2-propanol, ketyl radicals decayed by a second order reaction to yield pinacol (yield 45%); in contrast, in cyclohexane, they decayed by a second order reaction in the bulk, leading to the formation of pinacol (yield 21%), and by recombination with the cyclohexyl radical in the cage in an apparent first order reaction to generate an adduct (yield 10%). In a polar and non H-atom donor solvent such as acetonitrile, the zwitterionic diradical ( λ max = 460 nm) was formed in 0.6 μs with the final formation of an atypical dimer. Thus, two mechanisms of hydrogen atom transfer were observed. In the polar acetonitrile solvent, a two-step process occurred, where an electron was transferred first, followed by a proton. In the less polar 2-propanol and non-polar cyclohexane solvents, a one-step process occurred, where an electron and a proton were simultaneously transferred. A novel photochemical electron transfer step is observed when a heteroaromatic substituent is present in an aromatic ketone.