Details

Autor(en) / Beteiligte

• Yang, Xin-He
• Li, Jian-Ping
• Wang, Dong-Chao
• Xie, Ming-Sheng
• Qu, Gui-Rong
• Guo, Hai-Ming

Titel

Enantioselective dearomative [3+2] cycloaddition of 2-nitrobenzofurans with aldehyde-derived Morita-Baylis-Hillman carbonates

Ist Teil von

• Chemical communications (Cambridge, England), 2019-08, Vol.55 (62), p.9144-9147

Ort / Verlag

England: Royal Society of Chemistry

Erscheinungsjahr

2019

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• The phosphine-catalyzed asymmetric dearomative [3+2] cycloaddition of 2-nitrobenzofurans with aldehyde-derived Morita-Baylis-Hillman (MBH) carbonates or allenoate was developed. The reaction with MBH carbonates resulted in a series of cyclopentabenzofurans containing three contiguous stereocenters with good to high yields, diastereoselectivities and enantioselectivities. The use of allenoate also gave the target product with moderate enantioselectivity. The phosphine-catalyzed asymmetric dearomative [3+2] cycloaddition of 2-nitrobenzofurans with aldehyde-derived MBH carbonates or allenoates was developed.