Details

Autor(en) / Beteiligte

• Xie, Zhenda
• Yin, Biao
• Shen, Jiajie
• Hong, Danqi
• Zhu, Liquan
• Ge, Jingyan
• Zhu, Qing

Titel

A dual functional fluorogenic probe for visualization of intracellular pH and formaldehyde with distinct fluorescence signalsElectronic supplementary information (ESI) available: Experimental details, supplementary data, synthesis and characterization of compounds. See DOI: 10.1039/c8ob00989a

Erscheinungsjahr

2018-06

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• In this study, a single fluorescent probe ( DPFP ) containing a 1,8-naphthalimide dye and a homoallylamino group for imaging pH and formaldehyde (FA) has been developed that exhibits significant blue fluorescence ( λ em at 455 nm) under acidic pH conditions (pH < 7.0) and green fluorescence ( λ em at 555 nm) in the presence of FA, respectively. Furthermore, probe DPFP was successfully applied to image acidic lysosomes and exogenous or endogenous FA in living HeLa cells. We present a dual functional fluorescent probe ( DPFP ) for imaging pH and formaldehyde (FA) with distinct fluorescence signals.