Details

Autor(en) / Beteiligte

• Cui, Peng-Fei
• Zhuang, Wan-Ru
• Hu, Xi
• Xing, Lei
• Yu, Ru-Yi
• Qiao, Jian-Bin
• He, Yu-Jing
• Li, Fangyuan
• Ling, Daishun
• Jiang, Hu-Lin

Titel

A new strategy for hydrophobic drug delivery using a hydrophilic polymer equipped with stacking unitsElectronic supplementary information (ESI) available: Detailed experimental methods and additional data. See DOI: 10.1039/c8cc04363a

Erscheinungsjahr

2018-07

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• A highly hydrophilic polymer equipped with guanidinium groups was used to load aromatic ring-containing hydrophobic agent doxorubicin (DOX) via π-π interaction. The results have shown that the delivery system exhibited enhanced cellular uptake and antitumor efficiency compared with free drugs. This study opens new avenues for the application of hydrophilic polymers in drug delivery. A highly hydrophilic polymer was used to deliver aromatic ring-containing hydrophobic agent doxorubicin (DOX) via π-π interaction.