Details

Autor(en) / Beteiligte

• Li, Cong-Xiang
• Liu, Rui-Juan
• Yin, Kun
• Wen, Li-Rong
• Li, Ming

Titel

Synthesis of disulfides tethered pyrroles from β-ketothioamides via a bicyclization/ring-opening/oxidative coupling reactionElectronic supplementary information (ESI) available. CCDC 950534 and 1430509. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c7ob00655a

Erscheinungsjahr

2017-07

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• A DABCO-promoted three-component reaction of β-ketothioamides (KTAs), arylglyoxals and 2-cyanoacetates to construct disulfides tethered pyrroles by using air as an oxidant has been disclosed. Importantly, this protocol involves a tandem sequence that includes Knoevenagel condensation, Michael addition, N -cyclization, O -cyclization, ring-opening and oxidative coupling. A DABCO-promoted three-component reaction of β-ketothioamides, arylglyoxals and 2-cyanoacetate to construct disulfides tethered pyrroles has been developed.