Details

Autor(en) / Beteiligte

• Su, M
• Tomás-Gamasa, María
• Serdjukow, S
• Mayer, P
• Carell, T

Titel

Synthesis and properties of a Cu(ii) complexing pyrazole ligandoside in DNAElectronic supplementary information (ESI) available: Experimental procedures for 6-19 and substituted oligonucleotides, characterization data of compounds, crystallographic data, TM and CD experiments data and NMR spectra. CCDC 965412. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c3cc47561a

Erscheinungsjahr

2013-12

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• The development of metal base pairs is of immense importance for the construction of DNA nanostructures. Here we report the synthesis of a biaryl pyrazole-phenol nucleoside that forms in DNA a stable self-pair upon complexation of a Cu( ii ) ion. A sequence with five consecutive pyrazole nucleotides allows the complexation of five Cu( ii ) ions in a row. A novel pyrazole-phenol self-base pair was created that allows stacking of multiple Cu( ii ) ions in the DNA duplex.