Details

Autor(en) / Beteiligte

• Khan, Omair
• Raashid, Sheharyar
• Hashim, Muhammad
• Clements, Kevin
• Maheshwari, Sanjay
• Uddin, Syed Mohammad Mazhar
• Siriya, Pranay
• Vadsariya, Aftab
• Park, Patricia
• Pascal, William

Titel

Diagnosis of adrenocortical carcinoma with hypercortisolism in a patient presenting with hypokalemic metabolic alkalosis

Ist Teil von

• Journal of community hospital internal medicine perspectives, 2022-09, Vol.12 (5), p.114-118

Ort / Verlag

Greater Baltimore Medical Center

Erscheinungsjahr

2022

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• Adrenocortical carcinoma (ACC) is a rare malignancy with an estimated annual incidence of 0.7–2 cases per million. Most patients present with steroid hormone excess or abdominal mass effects, but 15% of patients with ACC are diagnosed incidentally. A careful history, physical exam, and pertinent lab investigations are necessary to reach the diagnosis. Surgical resection is the cornerstone of treatment in localized ACC; however, systemic chemotherapy with mitotane is preferred in patients with widespread disease or those who are not ideal candidates for surgery.