Diabetologia, 2022-11, Vol.65 (11), p.1854-1866
2022
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Details
- Autor(en) / Beteiligte
- Titel
- Precision medicine in type 1 diabetes
- Ist Teil von
- Diabetologia, 2022-11, Vol.65 (11), p.1854-1866
- Ort / Verlag
- Berlin/Heidelberg: Springer Berlin Heidelberg
- Erscheinungsjahr
- 2022
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- First envisioned by early diabetes clinicians, a person-centred approach to care was an aspirational goal that aimed to match insulin therapy to each individual’s unique requirements. In the 100 years since the discovery of insulin, this goal has evolved to include personalised approaches to type 1 diabetes diagnosis, treatment, prevention and prediction. These advances have been facilitated by the recognition of type 1 diabetes as an autoimmune disease and by advances in our understanding of diabetes pathophysiology, genetics and natural history, which have occurred in parallel with advancements in insulin delivery, glucose monitoring and tools for self-management. In this review, we discuss how these personalised approaches have improved diabetes care and how improved understanding of pathogenesis and human biology might inform precision medicine in the future. Graphical abstract
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0012-186X, 1432-0428eISSN: 1432-0428DOI: 10.1007/s00125-022-05778-3Titel-ID: cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9522741
- Format
- –
- Schlagworte
- Autoimmune diseases, Biology, Blood Glucose, Blood Glucose Self-Monitoring, Chronic illnesses, Diabetes, Diabetes mellitus (insulin dependent), Diabetes Mellitus, Type 1 - genetics, Diabetes Mellitus, Type 1 - therapy, Diabetes Mellitus, Type 2 - therapy, Disease prevention, Glucose monitoring, Human Physiology, Humans, Insulin, Insulin - therapeutic use, Internal Medicine, Medicine, Medicine & Public Health, Metabolic Diseases, Metabolism, Pathogenesis, Pathophysiology, Patient-centered care, Patients, Precision Medicine, Review