Details

Autor(en) / Beteiligte

• Jabbour, Pascal
• Dmytriw, Adam A
• Sweid, Ahmad
• Piotin, Michel
• Bekelis, Kimon
• Sourour, Nader
• Raz, Eytan
• Linfante, Italo
• Dabus, Guilherme
• Kole, Max
• Martínez-Galdámez, Mario
• Nimjee, Shahid M
• Lopes, Demetrius K
• Hassan, Ameer E
• Kan, Peter
• Ghorbani, Mohammad
• Levitt, Michael R
• Escalard, Simon
• Missios, Symeon
• Shapiro, Maksim
• Clarençon, Frédéric
• Elhorany, Mahmoud
• Vela-Duarte, Daniel
• Tahir, Rizwan A
• Youssef, Patrick P
• Pandey, Aditya S
• Starke, Robert M
• El Naamani, Kareem
• Abbas, Rawad
• Hammoud, Bassel
• Mansour, Ossama Y
• Galvan, Jorge
• Billingsley, Joshua T
• Mortazavi, Abolghasem
• Walker, Melanie
• Dibas, Mahmoud
• Settecase, Fabio
• Heran, Manraj K S
• Kuhn, Anna L
• Puri, Ajit S
• Menon, Bijoy K
• Sivakumar, Sanjeev
• Mowla, Ashkan
• D'Amato, Salvatore
• Zha, Alicia M
• Cooke, Daniel
• Goyal, Mayank
• Wu, Hannah
• Cohen, Jake
• Turkel-Parrella, David
• Xavier, Andrew
• Waqas, Muhammad
• Tutino, Vincent M
• Siddiqui, Adnan
• Gupta, Gaurav
• Nanda, Anil
• Khandelwal, Priyank
• Tiu, Cristina
• Portela, Pere C
• Perez de la Ossa, Natalia
• Urra, Xabier
• de Lera, Mercedes
• Arenillas, Juan F
• Ribo, Marc
• Requena, Manuel
• Piano, Mariangela
• Pero, Guglielmo
• De Sousa, Keith
• Al-Mufti, Fawaz
• Hashim, Zafar
• Nayak, Sanjeev
• Renieri, Leonardo
• Aziz-Sultan, Mohamed A
• Nguyen, Thanh N
• Feineigle, Patricia
• Patel, Aman B
• Siegler, James E
• Badih, Khodr
• Grossberg, Jonathan A
• Saad, Hassan
• Gooch, M Reid
• Herial, Nabeel A
• Rosenwasser, Robert H
• Tjoumakaris, Stavropoula
• Tiwari, Ambooj

Titel

Characteristics of a COVID-19 Cohort With Large Vessel Occlusion: A Multicenter International Study

Ist Teil von

• Neurosurgery, 2022-06, Vol.90 (6), p.725-733

Ort / Verlag

United States: Wolters Kluwer

Erscheinungsjahr

2022

Link zum Volltext

Quelle

Oxford Journals 2020 Medicine

Beschreibungen/Notizen

• The mechanisms and outcomes in coronavirus disease (COVID-19)-associated stroke are unique from those of non-COVID-19 stroke. To describe the efficacy and outcomes of acute revascularization of large vessel occlusion (LVO) in the setting of COVID-19 in an international cohort. We conducted an international multicenter retrospective study of consecutively admitted patients with COVID-19 with concomitant acute LVO across 50 comprehensive stroke centers. Our control group constituted historical controls of patients presenting with LVO and receiving a mechanical thrombectomy between January 2018 and December 2020. The total cohort was 575 patients with acute LVO; 194 patients had COVID-19 while 381 patients did not. Patients in the COVID-19 group were younger (62.5 vs 71.2; P < .001) and lacked vascular risk factors (49, 25.3% vs 54, 14.2%; P = .001). Modified thrombolysis in cerebral infarction 3 revascularization was less common in the COVID-19 group (74, 39.2% vs 252, 67.2%; P < .001). Poor functional outcome at discharge (defined as modified Ranklin Scale 3-6) was more common in the COVID-19 group (150, 79.8% vs 132, 66.7%; P = .004). COVID-19 was independently associated with a lower likelihood of achieving modified thrombolysis in cerebral infarction 3 (odds ratio [OR]: 0.4, 95% CI: 0.2-0.7; P < .001) and unfavorable outcomes (OR: 2.5, 95% CI: 1.4-4.5; P = .002). COVID-19 was an independent predictor of incomplete revascularization and poor outcomes in patients with stroke due to LVO. Patients with COVID-19 with LVO were younger, had fewer cerebrovascular risk factors, and suffered from higher morbidity/mortality rates.