Details

Autor(en) / Beteiligte

• Adedeji, Idris A
• Adamu, Adamu S
• Bashir, Faruk M

Titel

Factors associated with seizure severity among children with epilepsy in Northern Nigeria

Ist Teil von

• Ghana medical journal, 2022-03, Vol.56 (1), p.23-27

Ort / Verlag

Ghana Medical Association

Erscheinungsjahr

2022

Link zum Volltext

Quelle

EZB Free E-Journals

Beschreibungen/Notizen

• Objective: To describe how seizure severity in children with epilepsy may be affected by certain socio-demographic and clinical variablesDesign: A cross-sectional studySetting: At the Abubakar Tafawa Balewa University Teaching Hospital, Bauchi, NigeriaParticipants: Sixty children and adolescents who were being followed up for seizure disorder at the child neurology clinicIntervention: Information on socio-demographic characteristics was obtained with a questionnaire, details of neuro-logical co-morbidities were extracted from the participants’ records, and seizure severity was assessed with the Na-tional Hospital Seizure Severity Score 3 tool.Main Outcome Measure: Chi-square test was used to establish the relationship between categorical variables, while the Independent t-test was used in describing the differences between means. Simple linear regression was calculated to assess the predictability of seizure severity.Result: The median age was ten years (IQR = 6-13 years), with a male dominance (1.5:1). The Seizure Severity Score (SSS) ranged between 3 and 24 units, with a mean of 12.22 ± 4.29 units. The only characteristic that had a significant association with SSS on bivariate analysis was the “presence of co-morbidities” (p=0.019). A simple linear regression revealed that the presence of a neurological co-morbidity predicted an increase in the SSS by 2.67 units. [R2 = 0.091, F (1, 58)= 5.837, p = 0.019. ꞵ = 2.67, t= 2.42, p= 0.019.]Conclusion: This study shows that neurological co-morbidities predict worsening seizure severity. This knowledge may influence prognostication and the charting of a treatment trajectory.