UNIVERSI
TÄ
TS-
BIBLIOTHEK
P
ADERBORN
Anmelden
Menü
Menü
Start
Hilfe
Blog
Weitere Dienste
Neuerwerbungslisten
Fachsystematik Bücher
Erwerbungsvorschlag
Bestellung aus dem Magazin
Fernleihe
Einstellungen
Sprache
Deutsch
Deutsch
Englisch
Farbschema
Hell
Dunkel
Automatisch
Sie befinden Sich nicht im Netzwerk der Universität Paderborn. Der Zugriff auf elektronische Ressourcen ist
gegebenenfalls
nur via VPN oder Shibboleth (DFN-AAI) möglich.
mehr Informationen...
Universitätsbibliothek
Katalog
Suche
Details
Zur Ergebnisliste
Ergebnis 23 von 518
Datensatz exportieren als...
BibTeX
Best Performance Parameters of HR‐pQCT to Predict Fragility Fracture: Systematic Review and Meta‐Analysis
Journal of bone and mineral research, 2021-12, Vol.36 (12), p.2381-2398
Cheung, Wing‐Hoi
Hung, Vivian Wing‐Yin
Cheuk, Ka‐Yee
Chau, Wai‐Wang
Tsoi, Kelvin Kam‐Fai
Wong, Ronald Man‐Yeung
Chow, Simon Kwoon‐Ho
Lam, Tsz‐Ping
Yung, Patrick Shu‐Hang
Law, Sheung‐Wai
Qin, Ling
2021
Details
Autor(en) / Beteiligte
Cheung, Wing‐Hoi
Hung, Vivian Wing‐Yin
Cheuk, Ka‐Yee
Chau, Wai‐Wang
Tsoi, Kelvin Kam‐Fai
Wong, Ronald Man‐Yeung
Chow, Simon Kwoon‐Ho
Lam, Tsz‐Ping
Yung, Patrick Shu‐Hang
Law, Sheung‐Wai
Qin, Ling
Titel
Best Performance Parameters of HR‐pQCT to Predict Fragility Fracture: Systematic Review and Meta‐Analysis
Ist Teil von
Journal of bone and mineral research, 2021-12, Vol.36 (12), p.2381-2398
Ort / Verlag
Hoboken, USA: John Wiley & Sons, Inc
Erscheinungsjahr
2021
Link zum Volltext
Quelle
Wiley Online Library - AutoHoldings Journals
Beschreibungen/Notizen
ABSTRACT Osteoporosis is a systemic skeletal disease characterized by low bone mass and bone structural deterioration that may result in fragility fractures. Use of bone imaging modalities to accurately predict fragility fractures is always an important issue, yet the current gold standard of dual‐energy X‐ray absorptiometry (DXA) for diagnosis of osteoporosis cannot fully satisfy this purpose. The latest high‐resolution peripheral quantitative computed tomography (HR‐pQCT) is a three‐dimensional (3D) imaging device to measure not only volumetric bone density, but also the bone microarchitecture in a noninvasive manner that may provide a better fracture prediction power. This systematic review and meta‐analysis was designed to investigate which HR‐pQCT parameters at the distal radius and/or distal tibia could best predict fragility fractures. A systematic literature search was conducted in Embase, PubMed, and Web of Science with relevant keywords by two independent reviewers. Original clinical studies using HR‐pQCT to predict fragility fractures with available full text in English were included. Information was extracted from the included studies for further review. In total, 25 articles were included for the systematic review, and 16 articles for meta‐analysis. HR‐pQCT was shown to significantly predict incident fractures and/or major osteoporotic fractures (MOFs). Of all the HR‐pQCT parameters, our meta‐analysis revealed that cortical volumetric bone mineral density (Ct.vBMD), trabecular thickness (Tb.Th), and stiffness were better predictors. Meanwhile, HR‐pQCT parameters indicated better performance in predicting MOFs than incident fractures. Between the two standard measurement sites of HR‐pQCT, the non‐weight‐bearing distal radius was a more preferable site than distal tibia for fracture prediction. Furthermore, most of the included studies were white‐based, whereas very few studies were from Asia or South America. These regions should build up their densitometric databases and conduct related prediction studies. It is expected that HR‐pQCT can be used widely for the diagnosis of osteoporosis and prediction of future fragility fractures. © 2021 The Authors. Journal of Bone and Mineral Research published by Wiley Periodicals LLC on behalf of American Society for Bone and Mineral Research (ASBMR).
Sprache
Englisch
Identifikatoren
ISSN: 0884-0431
eISSN: 1523-4681
DOI: 10.1002/jbmr.4449
Titel-ID: cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9298023
Format
–
Schlagworte
Absorptiometry, Photon
,
Bone Density
,
Bone imaging
,
Bone mass
,
Bone mineral density
,
Computed tomography
,
Cortical bone
,
Diagnosis
,
Dual energy X-ray absorptiometry
,
Fractures
,
FRAGILITY FRACTURE
,
HR‐pQCT
,
Humans
,
META‐ANALYSIS
,
Original
,
OSTEOPOROSIS
,
Osteoporosis - diagnostic imaging
,
Osteoporotic Fractures - diagnostic imaging
,
Predictions
,
Radius
,
Radius - diagnostic imaging
,
Reviews
,
SYSTEMATIC REVIEW
,
Tibia
Weiterführende Literatur
Empfehlungen zum selben Thema automatisch vorgeschlagen von
bX