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Prospective Evaluation of Prostate and Organs at Risk Segmentation Software for MRI-based Prostate Radiation Therapy
Radiology. Artificial intelligence, 2022-03, Vol.4 (2), p.e210151
Sanders, Jeremiah W
Kudchadker, Rajat J
Tang, Chad
Mok, Henry
Venkatesan, Aradhana M
Thames, Howard D
Frank, Steven J
2022
Volltextzugriff (PDF)
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Autor(en) / Beteiligte
Sanders, Jeremiah W
Kudchadker, Rajat J
Tang, Chad
Mok, Henry
Venkatesan, Aradhana M
Thames, Howard D
Frank, Steven J
Titel
Prospective Evaluation of Prostate and Organs at Risk Segmentation Software for MRI-based Prostate Radiation Therapy
Ist Teil von
Radiology. Artificial intelligence, 2022-03, Vol.4 (2), p.e210151
Ort / Verlag
United States: Radiological Society of North America
Erscheinungsjahr
2022
Quelle
EZB Electronic Journals Library
Beschreibungen/Notizen
The segmentation of the prostate and surrounding organs at risk (OARs) is a necessary workflow step for performing dose-volume histogram analyses of prostate radiation therapy procedures. Low-dose-rate prostate brachytherapy (LDRPBT) is a curative prostate radiation therapy treatment that delivers a single fraction of radiation over a period of days. Prior studies have demonstrated the feasibility of fully convolutional networks to segment the prostate and surrounding OARs for LDRPBT dose-volume histogram analyses. However, performance evaluations have been limited to measures of global similarity between algorithm predictions and a reference. To date, the clinical use of automatic segmentation algorithms for LDRPBT has not been evaluated, to the authors' knowledge. The purpose of this work was to assess the performance of fully convolutional networks for prostate and OAR delineation on a prospectively identified cohort of patients who underwent LDRPBT by using clinically relevant metrics. Thirty patients underwent LDRPBT and were imaged with fully balanced steady-state free precession MRI after implantation. Custom automatic segmentation software was used to segment the prostate and four OARs. Dose-volume histogram analyses were performed by using both the original automatically generated contours and the physician-refined contours. Dosimetry parameters of the prostate, external urinary sphincter, and rectum were compared without and with the physician refinements. This study observed that physician refinements to the automatic contours did not significantly affect dosimetry parameters. MRI, Neural Networks, Radiation Therapy, Radiation Therapy/Oncology, Genital/Reproductive, Prostate, Segmentation, Dosimetry © RSNA, 2022.
Sprache
Englisch
Identifikatoren
ISSN: 2638-6100
eISSN: 2638-6100
DOI: 10.1148/ryai.210151
Titel-ID: cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8980936
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–
Schlagworte
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