The Journal of cell biology, 2022-04, Vol.221 (4), p.1
2022
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Details
- Autor(en) / Beteiligte
- Titel
- Non-canonical ubiquitylation makes its mark on Rap2 and cell motility
- Ist Teil von
- The Journal of cell biology, 2022-04, Vol.221 (4), p.1
- Ort / Verlag
- United States: Rockefeller University Press
- Erscheinungsjahr
- 2022
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Ubiquitin modification controls protein stability and cargo trafficking, and in this issue Duncan et al. (2022. J. Cell Biol.https://doi.org/10.1083/jcb.202107114) reveal a unique mechanism through which Rab40b/Cul5-mediated ubiquitylation of Rap2 regulates its activity and recycling to the leading edge to control cell migration and invasion.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0021-9525, 1540-8140eISSN: 1540-8140DOI: 10.1083/jcb.202203029Titel-ID: cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8961291
- Format
- –
- Schlagworte
- Biochemistry, Cancer, Cell Movement, Migration, Motility, Spotlight, Trafficking, Ubiquitin, Ubiquitination