Details

Autor(en) / Beteiligte

• Vasaghi Gharamaleki, Maryam
• Habibagahi, Maryam
• Hooshmandi, Etrat
• Tabrizi, Reza
• Arsang-Jang, Shahram
• Barzegar, Zohreh
• Fadakar, Nima
• Reza Ostovan, Vahid
• Rahimi-Jaberi, Abbas
• Ashjazadeh, Nahid
• Petramfar, Peyman
• Poursadeghfard, Maryam
• Izadi, Sadegh
• Nazeri, Masoumeh
• Bazrafshan, Hanieh
• Bahrami, Zahra
• Karimlu, Sedigheh
• Shaghayegh Zafarmand, Seyedeh
• Bayat, Mahnaz
• Saied Salehi, Mohammad
• Owjfard, Maryam
• Karimi-Haghighi, Saeideh
• Safari, Anahid
• Shakibajahromi, Banafsheh
• Lim Alvin Chew, Beng
• Worral, Bradford B. g
• Coutinho, Jonathan M.
• Garcia-Esperon, Carlos
• Spratt, Neil
• Levi, Christopher
• Azarpazhooh, Mahmoud Reza
• Borhani-Haghighi, Afshin

Titel

The Hospitalization Rate of Cerebral Venous Sinus Thrombosis before and during COVID-19 Pandemic Era: A Single-Center Retrospective Cohort Study

Ist Teil von

• Journal of stroke and cerebrovascular diseases, 2022-07, Vol.31 (7), p.106468-106468, Article 106468

Ort / Verlag

United States: Elsevier Inc

Erscheinungsjahr

2022

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• There are several reports of the association between SARS-CoV-2 infection (COVID-19) and cerebral venous sinus thrombosis (CVST). In this study, we aimed to compare the hospitalization rate of CVST before and during the COVID-19 pandemic (before vaccination program). In this retrospective cohort study, the hospitalization rate of adult CVST patients in Namazi hospital, a tertiary referral center in the south of Iran, was compared in two periods of time. We defined March 2018 to March 2019 as the pre-COVID-19 period and March 2020 to March 2021 as the COVID-19 period. 50 and 77 adult CVST patients were hospitalized in the pre-COVID-19 and COVID-19 periods, respectively. The crude CVST hospitalization rate increased from 14.33 in the pre-COVID-19 period to 21.7 per million in the COVID-19 era (P = 0.021). However, after age and sex adjustment, the incremental trend in hospitalization rate was not significant (95% CrI: -2.2, 5.14). Patients > 50-year-old were more often hospitalized in the COVID-19 period (P = 0.042). SARS-CoV-2 PCR test was done in 49.3% out of all COVID-19 period patients, which were positive in 6.5%. Modified Rankin Scale (mRS) score ≥3 at three-month follow-up was associated with age (P = 0.015) and malignancy (P = 0.014) in pre-COVID period; and was associated with age (P = 0.025), altered mental status on admission time (P<0.001), malignancy (P = 0.041) and COVID-19 infection (P = 0.008) in COVID-19 period. Since there was a more dismal outcome in COVID-19 associated CVST, a high index of suspicion for CVST among COVID-19 positive is recommended.