Details

Autor(en) / Beteiligte

• Viana, Raquel
• Moyo, Sikhulile
• Amoako, Daniel G
• Tegally, Houriiyah
• Scheepers, Cathrine
• Althaus, Christian L
• Anyaneji, Ugochukwu J
• Bester, Phillip A
• Boni, Maciej F
• Chand, Mohammed
• Choga, Wonderful T
• Colquhoun, Rachel
• Davids, Michaela
• Deforche, Koen
• Doolabh, Deelan
• du Plessis, Louis
• Engelbrecht, Susan
• Everatt, Josie
• Giandhari, Jennifer
• Giovanetti, Marta
• Hardie, Diana
• Hill, Verity
• Hsiao, Nei-Yuan
• Iranzadeh, Arash
• Ismail, Arshad
• Joseph, Charity
• Joseph, Rageema
• Koopile, Legodile
• Kosakovsky Pond, Sergei L
• Kraemer, Moritz U G
• Kuate-Lere, Lesego
• Laguda-Akingba, Oluwakemi
• Lesetedi-Mafoko, Onalethatha
• Lessells, Richard J
• Lockman, Shahin
• Lucaci, Alexander G
• Maharaj, Arisha
• Mahlangu, Boitshoko
• Maponga, Tongai
• Mahlakwane, Kamela
• Makatini, Zinhle
• Marais, Gert
• Maruapula, Dorcas
• Masupu, Kereng
• Matshaba, Mogomotsi
• Mayaphi, Simnikiwe
• Mbhele, Nokuzola
• Mbulawa, Mpaphi B
• Mendes, Adriano
• Mlisana, Koleka
• Mnguni, Anele
• Mohale, Thabo
• Moir, Monika
• Moruisi, Kgomotso
• Mosepele, Mosepele
• Motsatsi, Gerald
• Motswaledi, Modisa S
• Mphoyakgosi, Thongbotho
• Msomi, Nokukhanya
• Mwangi, Peter N
• Naidoo, Yeshnee
• Ntuli, Noxolo
• Nyaga, Martin
• Olubayo, Lucier
• Pillay, Sureshnee
• Radibe, Botshelo
• Ramphal, Yajna
• Ramphal, Upasana
• San, James E
• Scott, Lesley
• Shapiro, Roger
• Singh, Lavanya
• Smith-Lawrence, Pamela
• Stevens, Wendy
• Strydom, Amy
• Subramoney, Kathleen
• Tebeila, Naume
• Tshiabuila, Derek
• Tsui, Joseph
• van Wyk, Stephanie
• Weaver, Steven
• Wibmer, Constantinos K
• Wilkinson, Eduan
• Wolter, Nicole
• Zarebski, Alexander E
• Zuze, Boitumelo
• Goedhals, Dominique
• Preiser, Wolfgang
• Treurnicht, Florette
• Venter, Marietje
• Williamson, Carolyn
• Pybus, Oliver G
• Bhiman, Jinal
• Glass, Allison
• Martin, Darren P
• Rambaut, Andrew
• Gaseitsiwe, Simani
• von Gottberg, Anne
• de Oliveira, Tulio

Titel

Rapid epidemic expansion of the SARS-CoV-2 Omicron variant in southern Africa

Ist Teil von

• Nature (London), 2022-03, Vol.603 (7902), p.679-686

Ort / Verlag

England: Nature Publishing Group

Erscheinungsjahr

2022

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• The SARS-CoV-2 epidemic in southern Africa has been characterized by three distinct waves. The first was associated with a mix of SARS-CoV-2 lineages, while the second and third waves were driven by the Beta (B.1.351) and Delta (B.1.617.2) variants, respectively . In November 2021, genomic surveillance teams in South Africa and Botswana detected a new SARS-CoV-2 variant associated with a rapid resurgence of infections in Gauteng province, South Africa. Within three days of the first genome being uploaded, it was designated a variant of concern (Omicron, B.1.1.529) by the World Health Organization and, within three weeks, had been identified in 87 countries. The Omicron variant is exceptional for carrying over 30 mutations in the spike glycoprotein, which are predicted to influence antibody neutralization and spike function . Here we describe the genomic profile and early transmission dynamics of Omicron, highlighting the rapid spread in regions with high levels of population immunity.