Details

Autor(en) / Beteiligte

• Pollett, Simon D
• Richard, Stephanie A
• Fries, Anthony C
• Simons, Mark P
• Mende, Katrin
• Lalani, Tahaniyat
• Lee, Tida
• Chi, Sharon
• Mody, Rupal
• Madar, Cristian
• Ganesan, Anuradha
• Larson, Derek T
• Colombo, Christopher J
• Colombo, Rhonda
• Samuels, Emily C
• Broder, Christopher C
• Laing, Eric D
• Smith, Darci R
• Tribble, David
• Agan, Brian K
• Burgess, Timothy H

Titel

The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) mRNA Vaccine-Breakthrough Infection Phenotype Includes Significant Symptoms, Live Virus Shedding, and Viral Genetic Diversity

Ist Teil von

• Clinical infectious diseases, 2022-03, Vol.74 (5), p.897-900

Ort / Verlag

US: Oxford University Press

Erscheinungsjahr

2022

Quelle

Oxford Journals 2020 Medicine

Beschreibungen/Notizen

• Abstract Little is known about severe acute respiratory syndrome coronavirus 2 “vaccine-breakthrough” infections (VBIs). Here we characterize 24 VBIs in predominantly young healthy persons. While none required hospitalization, a proportion endorsed severe symptoms and shed live virus as high as 4.13 × 103 plaque-forming units/mL. Infecting genotypes included both variant-of-concern (VOC) and non-VOC strains.