Details

Autor(en) / Beteiligte

• Pajon, Rolando
• Doria-Rose, Nicole A
• Shen, Xiaoying
• Schmidt, Stephen D
• O’Dell, Sijy
• McDanal, Charlene
• Feng, Wenhong
• Tong, Jin
• Eaton, Amanda
• Maglinao, Maha
• Tang, Haili
• Manning, Kelly E
• Edara, Venkata-Viswanadh
• Lai, Lilin
• Ellis, Madison
• Moore, Kathryn M
• Floyd, Katharine
• Foster, Stephanie L
• Posavad, Christine M
• Atmar, Robert L
• Lyke, Kirsten E
• Zhou, Tongqing
• Wang, Lingshu
• Zhang, Yi
• Gaudinski, Martin R
• Black, Walker P
• Gordon, Ingelise
• Guech, Mercy
• Ledgerwood, Julie E
• Misasi, John N
• Widge, Alicia
• Sullivan, Nancy J
• Roberts, Paul C
• Beigel, John H
• Korber, Bette
• Baden, Lindsey R
• El Sahly, Hana
• Chalkias, Spyros
• Zhou, Honghong
• Feng, Jing
• Girard, Bethany
• Das, Rituparna
• Aunins, Anne
• Edwards, Darin K
• Suthar, Mehul S
• Mascola, John R
• Montefiori, David C

Titel

SARS-CoV-2 Omicron Variant Neutralization after mRNA-1273 Booster Vaccination

Ist Teil von

• The New England journal of medicine, 2022-03, Vol.386 (11), p.1088-1091

Ort / Verlag

United States: Massachusetts Medical Society

Erscheinungsjahr

2022

Link zum Volltext

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Neutralization of the omicron variant was assessed in serum samples obtained from persons who had received an mRNA-1273 booster. After the standard two-dose vaccine regimen, these titers were approximately 35 times lower than those against the D614G variant. However, boosters increased omicron neutralization by a factor of 20 — to levels that correlate with clinical resistance to infection.