BMJ case reports, 2022-01, Vol.15 (1), p.e246401
2022
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- Autor(en) / Beteiligte
- Titel
- Adalimumab-induced sensory vasculitic neuropathy
- Ist Teil von
- BMJ case reports, 2022-01, Vol.15 (1), p.e246401
- Ort / Verlag
- England: BMJ Publishing Group LTD
- Erscheinungsjahr
- 2022
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Vasculitis and other autoimmune conditions are known complications of tumour necrosis factor alpha (TNF-α) inhibitor use. By definition, TNF-α inhibitor induced vasculitis is a secondary systemic vasculitis. However, its phenotype is varied and can present as an isolated vasculitic neuropathy. This presents a diagnostic challenge as the gold standard for diagnosis of a vasculitic neuropathy is a peripheral nerve biopsy that meets predefined histopathological criteria. Given the poor sensitivity of the peripheral nerve biopsy, it is important that clinicians take a good history and maintain a high index of suspicion, as this is a treatable iatrogenic condition. Here we present a case of adalimumab-induced sensory vasculitic neuropathy, treated according to the Peripheral Nerve Society guideline for non-systemic vasculitic neuropathy, given her disease phenotype.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1757-790XeISSN: 1757-790XDOI: 10.1136/bcr-2021-246401Titel-ID: cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8768498
- Format
- –
- Schlagworte
- Adalimumab - adverse effects, Antibodies, Arthritis, Biopsy, Case Report, Case reports, Collaboration, Electromyography, Female, Hepatitis, HIV, Human immunodeficiency virus, Humans, Inflammation, Lymphocytes, Monoclonal antibodies, Pain, Peripheral Nervous System Diseases - chemically induced, Peripheral Nervous System Diseases - diagnosis, Systemic Vasculitis, TNF inhibitors, Tumor necrosis factor-TNF, Vasculitis - chemically induced, Vasculitis - diagnosis, Vitamin B